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Cambridge AS & A Level Biology

14.1Homeostasis in mammals

Homeostasis in mammals in Cambridge AS & A Level Biology: what the syllabus expects you to know, the learning objectives and how to practise.
Subtopic62 practice questions3 lessons

Learning objectives

What the syllabus expects you to be able to do.

  1. 14.1.1Explain what homeostasis is and why it matters in mammals.
  2. 14.1.2Explain homeostasis in terms of stimuli, receptors, nervous and endocrine coordination, effectors and negative feedback.
  3. 14.1.3State that urea is made in the liver by deamination of excess amino acids.
  4. 14.1.4Describe the structure of the kidney.
  5. 14.1.5Identify the parts of a nephron and its blood vessels.
  6. 14.1.6Describe and explain ultrafiltration in the Bowman's capsule and selective reabsorption in the proximal convoluted tubule.
  7. 14.1.7Relate the structure of the Bowman's capsule and proximal convoluted tubule to their functions.
  8. 14.1.8Describe the roles of the hypothalamus, posterior pituitary, ADH, aquaporins and collecting ducts in osmoregulation.
  9. 14.1.9Describe cell signalling by glucagon: receptor, G-protein, adenylyl cyclase, cAMP, protein kinase A and the amplifying enzyme cascade.
  10. 14.1.10Explain negative feedback control of blood glucose by insulin (muscle and liver) and glucagon (liver).
  11. 14.1.11Explain how test strips and biosensors measure glucose, with glucose oxidase and peroxidase.

Lessons

  • Control of blood glucose and cell signalling

    45 min

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  • Principles of homeostasis

    35 min

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  • The kidney: urine formation and osmoregulation

    50 min

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Sample question

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Homeostasis in mammals: sample question

1 mark

How does insulin increase the uptake of glucose by muscle cells?

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