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Cambridge AS & A Level Biology

6.2Protein synthesis

Protein synthesis in Cambridge AS & A Level Biology: what the syllabus expects you to know, the learning objectives and how to practise.
Subtopic57 practice questions3 lessons

Learning objectives

What the syllabus expects you to be able to do.

  1. 6.2.1State that a gene is a sequence of nucleotides in DNA that codes for a polypeptide.
  2. 6.2.2Describe the universal genetic code of triplets coding for amino acids, start and stop codons.
  3. 6.2.3Describe transcription and translation, with the roles of RNA polymerase, mRNA, codons, tRNA, anticodons and ribosomes.
  4. 6.2.4State that the transcribed strand is the template strand and the other the non-transcribed strand.
  5. 6.2.5Explain how introns are removed and exons joined to form eukaryotic mRNA.
  6. 6.2.6State that a gene mutation is a change in the base sequence that may alter a polypeptide.
  7. 6.2.7Explain substitution, deletion and insertion mutations and how each may affect the polypeptide.

Lessons

  • Gene mutations: types, effects and sickle cell anaemia

    35 min

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  • The genetic code and transcription

    30 min

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  • Translation: from mRNA to polypeptide

    35 min

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Sample question

A sample question on this topic. Answer it, check it, then read the worked answer.

Protein synthesis: sample question

1 mark

Why do many substitutions in the third base of a codon have no effect on the polypeptide?

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